Truckee Games offers many game worlds (and growing!). The worlds are presented without an attached rule set so that you may utilize them with your preferred game (though personally, I prefer ICRPG, Risus, and TinyD6).
Links on the side take you to downloadable documents and supplemental material.
Full Settings
Bamboo Age: After the Stone Age passed with the death of Gods, and before the Bronze Age brought the working of metals, there was the Bamboo Age.
Burning Synapse: Psychic alien symbiotes use human hosts on Earth to wage an eternal war across dimensions and time.
Destroyer of Worlds: An epic sci-fi spiritual saga of a people who are born, die, and are reborn over thousands of years, and keep making the same mistakes
The Devil Is: Gangland horror in the early 20th century, but is the horror man-made or from the Devil itself? Is it real, imagined, or have you gone insane? Time will tell, if you live that long.
Full Contact Magic: Full Contact Magic is a fantasy themed setting replete with elves and dwarves and halflings...but also a myriad of other races to play, and magic, and then there are magical mecha and tanks, and moons full of monsters. Confused? You'll figure it all out soon enough.
Future Imperfect: Long after the last human was born, sentient robots attempt to find a way to resurrect humanity and save themselves as they too face extinction in an increasingly dangerous world.
Gears & Gaslights: Eradicating spirits and manifestations for fame and profit in the Victorian-Era with steampunk-like devices powered by ghost energy.
Murder...for any Occasion: Not exactly a setting on it's own, but rather an examination of cozy
mysteries: Usually defined as a light-hearted and
charming murder mystery.
The Mythic West: In the old west, across seven Earths, people attempt to catch Coyote to put the worlds back in unity. That is, if The Devil's agents don't kill the heroes first.
Terra Mutant: Part science, part fantasy, but all apocalyptic wackiness. If you like TSR's Gamma World, you'll like Terra Mutant.